We focus broadly on the role of brain mitochondrial function in social behavior. As social dysfunction is a key component of several different disorders, we ask questions about a wide variety of diseases, including depression, anxiety, autism spectrum disorders, and Gulf War Illness.
Currently funded projects:
Role of amygdala in social and emotional behaviors in Fragile X Syndrome
In collaboration with the Mott and Klusek labs, we combine electrophysiology with behavior to investigate the role of the Fragile X Mental Retardation Protein (FMRP) in the amygdala to FXS-related behaviors. This work is funded by a SCAND pilot grant through the SCAND network.
Role of mitochondrial function in Gulf War Illness
We collaborate with the Reagan lab to examine how stress and pyridostigmine bromide exposure affects mitochondrial function in the brain and periphery and relate to anxiety-like and social behaviors. This work is funded by a VISN7 research development award from the VA.
Mitochondrial mechanisms and nutritional interventions for brain aging and memory
We collaborate with the McQuail lab to examine how aging and diet affects mitochondrial function in the brain and periphery and relate to cognitive function. This work is funded by a P20 targeted faculty pilot grant from the NIGMS.